Endocrine Abstracts

Introduction: Diabetes leads to skeletal fragility and an increased fracture risk. As a master regulator of bone-remodeling, osteocyte dysfunction may play a role in the pathogenesis of diabetes-related skeletal fragility. To study the effects of hyperglycemia on the osteocyte in-isolation, we used the osteocyte-like cell line IDG-SW3 taking an unbiased multi-omics-based approach.Methods: IDG-SW3 cells were plated in a differentiation osteogenic medium u...

Introduction: IPSS (Inferior petrosal sinus sampling) is a reliable test for differentiating Cushing’s disease from ectopic ACTH secretion. In the past 30 years, Hadassah Hebrew University Hospital has been the sole national referral center for IPSS in Israel, carrying out the test for all patients country-wide.Methods: In this retrospective study we reviewed the records of all patients who underwent IPSS in our institution, for whom electronic dat...